Friday, 15 Nov 2024

UK scientists’ discovery which could be the secret weapon in fight against coronavirus

Academics have discovered an antibody in the blood of a patient with Severe Acute Respiratory Syndrome (SARS), which they hope could neutralise the deadly coronavirus, which is sweeping across the globe at an alarming rate.  Scientists from non-profit organisation Diamond, in Harwell, Oxfordshire, used an X-ray machine, which works like a giant microscope, to analyse the blood of a patient who previously had SARS.

They found the antibody in the patient that was diagnosed with SARS in 2004 using the Diamond Light Source, a powerful machine which uses electrons to produce light beams to enable scientists to investigate viruses.

They found that the person had an antibody, which could cling onto a virus and fight it using the body’s natural immune defences.

Diamond’s deputy life sciences director, Professor Gwyndaf Evans revealed that the antibody latched on to the coronavirus even better than it had done with SARS.

He told The Daily Telegraph: ”Coronavirus has a spherical body with spikes coming out of the surface and it gets the name because of the shape of the spike, because it looks like a crown.

“The team has isolated the spike protein and looked at the surviving SARS patient to see if they can identify an antibody binding in the right place that has the potential to be useful.

“We found one that looks even better for binding to coronavirus, so we’re hoping it could become a therapy.”

SARS originated in China and outbreak, between November 2002 and July 2003, sparked 8,098 cases and 774 deaths reported in 17 countries.

Meanwhile scientists at Oxford University have developed a new coronavirus test which can give results in just half an hour – dramatically speeding up the rate at which possible sufferers of COVID-19 are diagnosed.

A team led by Professors Zhanfeng Cui and Wei Huang have also been working to improve test capabilities as the virus spreads across the world.

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Their new test is much faster, and does not require complicated instrumentation.

Whereas previous viral RNA tests took between one-and-a-half and two hours to provide a result, the research team has developed a new test, based on a technique capable of giving results in just half an hour – more than three times faster than the current method.

Prof Huang says: “The beauty of this new test lies in the design of the viral detection that can specifically recognise SARS-CoV-2 (COVID-19) RNA and RNA fragments.

“The test has built-in checks to prevent false positives or negatives and the results have been highly accurate.”

The virus has infected more than 245,000 people across the world and the death toll exceeds 10,028.

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