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The findings are based on data gathered from King’s College London’s COVID Symptom Study app. The researchers used the data to develop a model to predict which patients are most likely to require hospitalisation and breathing support based on their earliest symptoms.

A continuous cough, fever and loss of smell are usually highlighted as the three main symptoms of COVID-19.

But data gathered from around 1,600 users of the app shows a range of symptoms including headaches, muscle pains, fatigue, diarrhoea, confusion, loss of appetite and shortness of breath.

Dr Claire Steves from King’s College London said: “These findings have important implications for care and monitoring of people who are most vulnerable to severe COVID-19.

“If you can predict who these people are at day five, you have time to give them support and early interventions such as monitoring blood oxygen and sugar levels, and ensuring they are properly hydrated – simple care that could be given at home, preventing hospitalisations and saving lives.”

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7.45am update: PM plays down prospect of second national coronavirus lockdown

Boris Johnson has played down the prospect of a second national lockdown insisting he did not want to use it any more than Britain’s Trident nuclear deterrent.

The Prime Minister said the authorities were getting better at identifying and isolating local outbreaks but added it was important that the power to order national action was held in reserve.

Mr Johnson told The Sunday Telegraph: “I can’t abandon that tool any more than I would abandon a nuclear deterrent.

“But it is like a nuclear deterrent, I certainly don’t want to use it. And nor do I think we will be in that position again.”

7.30am update: Germany coronavirus cases rise by 202

Germany’s confirmed coronavirus cases have risen by 202 to 201,574, according to the latest figures from the Robert Koch Institute (RKI) for infectious diseases.

The country’s death toll rose by 1 to 9,084.

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