Boris Johnson’s younger brother resigned on Thursday after serving as a Conservative MP for nine years. The resignation is being seen as an extraordinary blow for the Prime Minister, who is struggling to keep Brexit under control and has already lost a significant number of MPs. The younger brother cited an “unresolvable tension” between “family loyalty and the national interest”.

He wrote on Twitter: “It’s been an honour to represent Orpington for nine years and to serve as a minster under three PMs.

“In recent weeks I’ve been torn between family loyalty and the national interest – it’s an unresolvable tension.”

Jo, who will stand down as an MP at the next general election, attended the Cabinet in his role as Universities Minister.

It is the second time he has quit Government in only 20 months because of his pro-EU views.

Last November, Mr Johnson resigned in protest at Theresa May’s Brexit strategy and in order to campaign for a second EU referendum.

According to a newly-resurfaced report by the Daily Telegraph, the Remainer Johnson went as far as to suggest that Brexit happened due to the “uneducated people in Britain”.

In 2016, the Universities Minister said there was “correlation” between levels of “education generally” and a “propensity” to vote Brexit.

He told a ConservativeHome event at the Tory conference: “If there was an overriding lesson from the referendum result on June 23, it was that too many people in this country felt they hadn’t been participating on a level footing.

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“Too many people were feeling they are not sharing equally in the benefits of growth.

“Too many people basically feeling left behind.

“There was a correlation between levels of university attendance and a propensity to vote Brexit.

“There was a correlation between levels of education generally and a likelihood for voting for Brexit.

“Which means there’s a huge opportunity for universities to play the part they want to play in widening participation and ensuring that more people, particularly from disadvantaged background, get a chance to go to university and share in the benefits that higher education can bring.”

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The Johnsons are not the first relatives on the frontline politics to disagree.

Ed and David Miliband rose through the ranks of the then-Labour government to seats at the Cabinet table and were seen as the party’s future.

David was Foreign Secretary and Ed was Secretary of State for Energy and Climate Change when Labour lost power in May 2010.

In the subsequent party leadership election that year, both siblings decided to run – with newspapers constantly reporting their rival bids.

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