WASHINGTON — The Trump administration, scrambling to make up for lost time after a halting start, is rushing to roll out a $250 million public education campaign to encourage Americans to take the coronavirus vaccine, which will reach the first patients in the United States this week.

Federal officials acknowledge the effort will be a complicated one. It must compete with public doubt and mistrust of government programs amid deep political divisions created in part by a president who has spent much of the year belittling government scientists, promoting ineffective treatments and dismissing the seriousness of the pandemic — and is now rushing to claim credit for a vaccine that he has made a priority.

“When you have an anti-science element together with a divisiveness in the country, it will be challenging,” Dr. Anthony S. Fauci, the government’s top infectious disease expert, said in an interview on Friday, while declining to talk specifically about President Trump. “But you know, we’ve done challenging things before.”

The Building Vaccine Confidence campaign, overseen by the Department of Health and Human Services, will unfold in an atmosphere of hope as vaccinations begin — but also despair as daily death tolls from Covid-19 approach 2,500 and the United States nears 300,000 total deaths. The campaign is part of a broader public relations effort that was initially supposed to feature celebrities whom the administration considered friendly to the president but came under scrutiny from Democrats who called it a propaganda campaign intended to re-elect Mr. Trump.

The celebrity component — which was to include the actor Dennis Quaid and the country singer Billy Ray Cyrus — was scrapped after an inquiry by House Democrats prompted Alex M. Azar II, the health secretary, to order an internal review of the plan. The new initiative will take a “science-based approach,” said Mark Weber, the federal health official who is running it, and will begin this week with a first wave of advertisements in print, social media and radio, with television advertising added when the vaccine becomes more broadly available.

That six-week hold ended when Mr. Azar’s review wrapped up on Nov. 13, but now, with vaccinations expected to begin Monday, the campaign is on an extremely tight timeline. Focus groups designed to help officials fine-tune the advertising to tailor it to hard-hit communities will begin Tuesday.

The effort — developed by Fors Marsh Group, a market research group, under contract with the government — is focused on what officials are calling the movable middle: people who are hesitant to take the vaccine, but who can be persuaded to do so. But that will not be an easy task.

“I have advised my team that we recognize our operating environment is complicated, we have a public health mission, and we need to stay focused on that,” said Mr. Weber, a 30-year career government official who has a master’s degree in marketing. He acknowledged that the campaign was battling “a credibility factor right now,” with a high level of distrust in government and fears about the safety of a vaccine that was produced in record time.

A majority of Americans — 60 percent — now say they will “definitely or probably” get a coronavirus vaccine, according to a survey released this month by the Pew Research Center. But strong anti-vaccination sentiment remains: 21 percent of American adults do not intend to be vaccinated and are “pretty certain” more information will not change their minds, the survey found.

Recent surveys show that women are more apprehensive about vaccination than men, with Black Americans the most hesitant group by race. Health officials are aware that they must dispel doubts about safety and enduring concerns over examples of unethical medical research in the United States, especially in African-American, Latino and Native American communities that have been hit especially hard by the coronavirus.

Even health care workers, who otherwise have among the highest rates of vaccine uptake, are apprehensive: In a survey in October by the American Nurses Foundation about a coronavirus vaccine, 37 percent said they were “not confident” that it would be safe and effective; 48 percent were “somewhat confident.”

Partisanship plays a role; Democrats are now more likely to want to be vaccinated than Republicans. In the fall, as Mr. Trump promised that a vaccine could be ready around Election Day, confidence among Republicans grew as did distrust among Democrats, but those trends have effectively flipped with the President-elect Joseph R. Biden Jr.’s victory, said Matthew Motta, a political scientist at Oklahoma State University who studies politics and vaccine intentionality.

“That implies that our intentions to vaccinate are very much tied to what our political leaders are saying,” Mr. Motta said. “So a bipartisan messaging strategy is very much needed.”

One of the biggest questions is what presence Mr. Trump will have. He has been eager to claim credit for driving the development of a vaccine in record time and does not want to share that recognition with his successor.

But Mr. Trump’s role in promoting vaccination would be extremely contentious. It would come after months in which he played down the threat of the virus, railed against common-sense measures like mask wearing to slow the spread of the disease and embraced bogus therapeutics that health professionals said were unproven and potentially dangerous.

“There is a bit of a whipsaw effect,” said Joel White, a Republican strategist who focuses on health policy. “If Trump is out there making a big stink about people getting the vaccine and needing to do it, I could see Democrats being turned off — and Blacks and Latinos in particular. But if he does nothing, then the Trump supporters might not be vaccinated because they would see that as a sign.”

Because the president has had Covid-19, he technically should be at the back of the line of people waiting for shots, but the sight of him being injected could be useful. At the White House, officials said having Mr. Trump take the vaccine publicly was “certainly under consideration,” though they noted that it might not affect public opinion since people know he has recovered. (Experts say that those who have survived Covid-19 may be at risk for re-infection and could benefit from vaccination.)

Dr. Fauci, for his part, intends to “get vaccinated publicly,” he said on Friday, as “soon as the vaccine becomes available to me,” as a way of shoring up public support. Aides to Vice President Mike Pence are deliberating about when and how he will be inoculated and whether he would do it in public.

Mr. Trump’s three presidential predecessors — Barack Obama, George W. Bush and Bill Clinton — have all said they are willing to be vaccinated on camera. In 2009, Mr. Obama and his wife, Michelle, made a public show of getting vaccinated against the H1N1 influenza virus, waiting their turn until after children had been given the vaccine.

“People need to understand that this vaccine is safe,” Mr. Obama said then. The White House website posted a photograph of him rolling up his sleeve for the shot.

Mr. Biden is already using his platform to encourage Americans to be vaccinated.

“I want to make it clear to the public: You should have confidence in this,” he said on Friday at an event in Wilmington, Del. “There is no political influence. These are first-rate scientists taking their time looking at all of the elements that need to be looked at. Scientific integrity led us to this point.”

Dr. David A. Kessler, a former commissioner of the Food and Drug Administration who advises the president-elect on the pandemic, said in an interview that the Biden team was working with medical organizations and other groups to come up with “the most creative, transparent and effective ways” to educate the public, including using a “range of respected voices — both local and national.”

Alongside that effort will be an equally important campaign aimed at doctors and professionals to whom patients will turn for advice. That was crucial, Dr. Kessler said, in ensuring that ordinary people were confident in the vaccine.

The Centers for Disease Control and Prevention says it will run its own effort to educate medical professionals; it is planning an online vaccine safety seminar for doctors and clinicians on Monday.

The Road to a Coronavirus Vaccine ›

Answers to Your Vaccine Questions

With distribution of a coronavirus vaccine beginning in the U.S., here are answers to some questions you may be wondering about:

• • If I live in the U.S., when can I get the vaccine? While the exact order of vaccine recipients may vary by state, most will likely put medical workers and residents of long-term care facilities first. If you want to understand how this decision is getting made, this article will help.
  • When can I return to normal life after being vaccinated? Life will return to normal only when society as a whole gains enough protection against the coronavirus. Once countries authorize a vaccine, they’ll only be able to vaccinate a few percent of their citizens at most in the first couple months. The unvaccinated majority will still remain vulnerable to getting infected. A growing number of coronavirus vaccines are showing robust protection against becoming sick. But it’s also possible for people to spread the virus without even knowing they’re infected because they experience only mild symptoms or none at all. Scientists don’t yet know if the vaccines also block the transmission of the coronavirus. So for the time being, even vaccinated people will need to wear masks, avoid indoor crowds, and so on. Once enough people get vaccinated, it will become very difficult for the coronavirus to find vulnerable people to infect. Depending on how quickly we as a society achieve that goal, life might start approaching something like normal by the fall 2021.
  • If I’ve been vaccinated, do I still need to wear a mask? Yes, but not forever. The two vaccines that will potentially get authorized this month clearly protect people from getting sick with Covid-19. But the clinical trials that delivered these results were not designed to determine whether vaccinated people could still spread the coronavirus without developing symptoms. That remains a possibility. We know that people who are naturally infected by the coronavirus can spread it while they’re not experiencing any cough or other symptoms. Researchers will be intensely studying this question as the vaccines roll out. In the meantime, even vaccinated people will need to think of themselves as possible spreaders.
  • Will it hurt? What are the side effects? The Pfizer and BioNTech vaccine is delivered as a shot in the arm, like other typical vaccines. The injection won’t be any different from ones you’ve gotten before. Tens of thousands of people have already received the vaccines, and none of them have reported any serious health problems. But some of them have felt short-lived discomfort, including aches and flu-like symptoms that typically last a day. It’s possible that people may need to plan to take a day off work or school after the second shot. While these experiences aren’t pleasant, they are a good sign: they are the result of your own immune system encountering the vaccine and mounting a potent response that will provide long-lasting immunity.
  • Will mRNA vaccines change my genes? No. The vaccines from Moderna and Pfizer use a genetic molecule to prime the immune system. That molecule, known as mRNA, is eventually destroyed by the body. The mRNA is packaged in an oily bubble that can fuse to a cell, allowing the molecule to slip in. The cell uses the mRNA to make proteins from the coronavirus, which can stimulate the immune system. At any moment, each of our cells may contain hundreds of thousands of mRNA molecules, which they produce in order to make proteins of their own. Once those proteins are made, our cells then shred the mRNA with special enzymes. The mRNA molecules our cells make can only survive a matter of minutes. The mRNA in vaccines is engineered to withstand the cell’s enzymes a bit longer, so that the cells can make extra virus proteins and prompt a stronger immune response. But the mRNA can only last for a few days at most before they are destroyed.

  Source: Read Full Article