Atea Pharma Says FDA Grants Fast Track Designation To AT-752 For Treatment Of Dengue

Biopharmaceutical company Atea Pharmaceuticals, Inc. (AVIR) announced Monday that the U.S. Food and Drug Administration (FDA) has granted Fast Track Designation to AT-752, a novel, orally administered, direct-acting antiviral for the treatment of dengue virus infection.

AT-752, a novel, orally administered direct-acting antiviral derived from Atea’s purine nucleotide prodrug platform was designed for the treatment and prophylaxis of dengue. It works by impairing the dengue viral polymerase, which then inhibits replication of the virus.

AT-752 is in Phase 2 clinical development and was generally well tolerated in a Phase 1 clinical study. In preclinical studies, AT-752 showed potent in vitro activity against all dengue serotypes, as well as potent in vivo antiviral activity in a small animal model.

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U.S. Covid Cases Fall 29% In Last Fortnight

Known coronavirus positive cases in the United States have fallen significantly in the last two weeks, by 29 percent, according to the New York Times’ latest data.

A 6 percent decrease was recorded in Covid casualties in the country during the same period.

With 450 additional deaths reported on Sunday, the total number of people that have lost their lives due to coronavirus infection in the country has risen to 1,053,436, as per Johns Hopkins University’s latest data.

4,710 new infections on the same day took the total U.S. Covid cases to 95,662,304.

New Jersey reported the most number of deaths – 150 – while New York recorded the most cases.

509 additional deaths were reported globally on Sunday, taking the total number of people who have lost their lives due to the pandemic so far to 6,526,738.

93,968,872 people have so far recovered from the disease, the Worldometer tally shows.

U.S. hospitals reported a 12 percent decrease in the number of Covid patients in the last two weeks. The number of I.C.U. admissions due to the worse stage of the viral disease has also fallen by 10 percent.

U.S. Covid hospitalizations fell to 31,794. 3,887 of these patients are admitted in intensive care units.

The nation’s current test positivity rate is 11 percent.

ApolloMed Announces Investment And Partnership With AAMG And FYB

Apollo Medical Holdings, Inc. (AMEH) said the company and its affiliated California medical corporation have entered into a definitive agreement to acquire 100% of the fully diluted capitalization of All American Medical Group and For Your Benefit, Inc., as well as certain related managed care assets. With the addition, ApolloMed will serve over 30,000 members in the San Francisco Bay Area.

AAMG is a primary and specialty care physicians’ group focused on providing culturally competent care to local communities in the San Francisco Bay Area. FYB is affiliated with AAMG and is licensed by the California Department of Managed Health Care as a full-service Restricted Knox-Keene licensed health plan.

Giorgia Meloni Set To Become Italy’s First Female Prime Minister

Giorgia Meloni is set to become Italy’s first female prime minister as the right-wing alliance led by her Brothers of Italy party is on course to win the general election.

With 63 percent of votes counted, the alliance has won more than 43 percent, according to the Italian Interior Ministry. Matteo Salvini’s League and former Prime Minister Silvio Berlusconi’s Forza Italia are the other parties in the alliance.

Addressing the media to claim victory, Meloni promised to govern for all Italians and said she would not betray their trust.

“It’s a victory I want to dedicate to everyone who is no longer with us and wanted this night,” she said. “Starting tomorrow we have to show our value … Italians chose us, and we will not betray it, as we never have,” she told reporters.

The Interior Ministry is expected to declare final results later in the day, but it will take weeks for a new government to be formed, reports say.

A member of the Chamber of Deputies since 2006, 45-year-old Meloni has also worked as a journalist.

She will be leading Italy’s most far-right government since the fascist Benito Mussolini.

Italy voted in another parliamentary election because Mario Draghi resigned as Prime Minister of the unity government after losing support of key allies in July.

European Economics Preview: Germany Ifo Business Confidence Data Due

Business confidence survey data from Germany is due on Monday, headlining a light day for the European economic news.

At 1.00 am ET, Statistics Finland releases import price figures for August. Prices had advanced 32.5 percent annually in July.

At 3.00 am ET, the Czech Statistical Office is scheduled to issue business and consumer confidence survey results.

At 4.00 am ET, Germany’s ifo business confidence survey data is due. The business sentiment index is expected to fall to 87.0 in September from 88.5 in the previous month.

ACM Research Stock Slips 11%

Shares of ACM Research, Inc. (ACMR) are slipping over 11% on Monday despite no stock-related news to hurt the shares.

ACMR is currently trading at $12.23, down $1.56 or 11.31%, on the Nasdaq. The stock opened its trading at $13.35 after closing Friday’s trading at $13.79. The stock has traded between $11.23 and $39.71 in the past 52-week period.

ACM Research, Inc., together with its subsidiaries, develops, manufactures, and sells single-wafer wet cleaning equipment for enhancing the manufacturing process and yield for integrated chips worldwide.

Queen Elizabeth Laid To Rest

Britain’s longest-reigning monarch Queen Elizabeth II was laid to rest after a state funeral in London Monday.

The Queen was buried at the King George VI Memorial Chapel near the Windsor Castle, next to her late husband Prince Philip.

Several leaders and dignitaries from around the world, including U.S President Joe Biden and French President Immanuel Macron, joined new King Charles III and the rest of the royal family at Westminster Abbey for the funeral service.

The Queen died on September 8, prompting an outpouring of grief across the UK and around the world.

Elizabeth, who came to the throne in 1952, died at the age of 96 after reigning for seven decades.

Her eldest son Charles succeeds her to the throne and as the new King of 14 Commonwealth realms.

Earlier, delivering remarks after signing the Official Condolence Book for the late Queen at Lancaster House, President Biden said, “Our hearts go out to the Royal Family — King Charles and all the family. It’s a loss that leaves a giant hole”.