UK Prime Minister Theresa May stepped out of 10 Downing Street at about 7.15pm on Wednesday following a marathon five-hour Cabinet meeting and announced the Cabinet had agreed the draft Brexit withdrawal agreement.

Here are the key developments since.

Wednesday, November 14

– 7.15pm – Prime Minister Theresa May makes a statement outside 10 Downing Street following a five-hour Cabinet meeting, announcing ministers have agreed the draft Brexit withdrawal agreement.

She said: “The choices before us were difficult, particularly in relation to the Northern Ireland backstop, but the collective decision of Cabinet was that the Government should agree the draft withdrawal agreement and the outline political declaration.”

– 8pm – Jean-Claude Juncker, President of the European Commission, writes to European Council President Donald Tusk to say that the withdrawal negotiations had concluded and the next step in the process can begin.

Thursday, November 15

– 7.30am – Donald Tusk announces the council will hold an extraordinary summit in Brussels on November 25 to finalise the UK’s withdrawal agreement.

– 7.30am – Shailesh Vara quits as Northern Ireland Minister.

– 8.50am – Brexit Secretary Dominic Raab quits.

– 10am – Work and Pensions Secretary Esther McVey resigns.

– 10.20am – Suella Braverman resigns as a Brexit minister.

– 10.20am – Anne-Marie Trevelyan quits as a parliamentary private secretary in the Department for Education.

– 10.30am – Mrs May begins her address to Parliament

– 12.35 – Ranil Jayawardena, Parliamentary Private Secretary at the Ministry of Justice, resigns.

– 1pm – Tories in the European Research Group meet in the House of Commons to discuss their response to Mrs May’s deal.

– 1.20pm – European Research Group chairman Jacob Rees-Mogg hands in his letter of no confidence to Sir Graham Brady, chairman of the 1922 Committee.

– 1.30pm – Mrs May finishes her statement to the Commons after nearly three hours, and after answering more than 100 questions.

– 1.55pm – Commons Leader and pro-Brexit MP Andrea Leadsom insists she has no plans to quit the Cabinet.

– 2.05pm – Further Tory MPs begin publishing letters of no confidence in Mrs May on Twitter.

– 3pm – Gillingham and Rainham MP Rehman Chishti resigns as Conservative vice-chairman and prime ministerial trade envoy to Pakistan.

– 5pm – Theresa May gives statement to the media – saying she will stick to her Brexit plan. She says she has always acted in the national interest, not in the partisan interest “and certainly” not in her personal interest.

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