The C.D.C. now says it is safe for fully vaccinated people to take their masks off in most indoor settings. States, cities and businesses were sorting through what to do with the guidance.

By Mitch Smith, Sarah Mervosh and Julie Bosman

More than a year after federal health officials told Americans to cover their faces when venturing out in public, the Centers for Disease Control and Prevention said on Thursday that fully vaccinated people could start taking off their masks indoors.

But the new federal guidance — announced amid a sharp decline in coronavirus cases and an expansion of vaccine eligibility to everyone 12 and older — came with caveats and confusion. And it sent state and local officials, as well as private companies, scrambling to decide whether and when to update their own rules.

Here are some questions you might have about what the C.D.C.’s new stance means, and what it doesn’t mean.

Does this mean masks are no longer recommended anywhere?

Not quite.

The federal guidance is expansive: Fully vaccinated people — those who have received their final Covid-19 vaccination at least two weeks ago — no longer need to wear masks outdoors or in most indoor settings. But there are limits.

The agency was not specific about masking in some settings, including schools. And even fully vaccinated people are still told to cover their faces when visiting health care facilities, while flying or taking public transit, and in congregate settings such as homeless shelters, as well as prisons or jails.

What does this mean for local mask mandates?

The C.D.C. advice does not override mask orders issued by states, counties or cities. But in the hours after the new policy was announced on Thursday, officials in some parts of the country began to adjust their rules to align with federal guidance. Others had yet to weigh in publicly, and some said they were keeping their rules in place while they reviewed the C.D.C.’s suggestions.

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